#create a screen with session name cli
screen -S cli

now detach, and let's control it entirely from another terminal
scr="screen -S cli"

#create a second window
$scr -X screen
#and a third
$scr -X screen
#select the first
$scr -X select 0
#split into two regions
$scr -X split
#focus on the lower one
$scr -X focus down
#select the second window in this lower region
$scr -X select 1
#clear window 0, leaving lower region showing window 1 and remaining current
$scr -p 0 -X clear
#greet window 0
$scr -p 0 -X exec echo hallo
#ssh to localhost in window 0
$scr -p 0 -X exec ssh localhost
#the exec hasn't returned
#simulate typing ls\n
$scr -p 0 -X register 1 "ls
"
$scr -p 0 -X paste 1
#that effectively ran ls on the remote host
#exit from the ssh connection
$scr -p 0 -X register 1 "exit
"
$scr -p 0 -X paste 1
#kill all three windows, terminating screen
$scr -p 2 -X kill
$scr -p 1 -X kill
$scr -p 0 -X kill